藥物交互作用
Apixaban + Berotralstat
嚴重程度: 中度
Apixaban and Berotralstat: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Berotralstat inhibits P-gp and may increase apixaban exposure. This could raise bleeding risk.
用白話說明這項交互作用的意義
Apixaban and Berotralstat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Apixaban belongs to Cardiovascular; Berotralstat belongs to Miscellaneous.
為什麼會發生
Inhibition of intestinal and renal P-gp efflux raises apixaban levels.
處置方式
Monitor for signs of bleeding, particularly in patients with renal impairment or low body weight.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Apixaban 的其他交互作用
Berotralstat 的其他交互作用
常見問題
Can I take Apixaban with Berotralstat?
MediHelp rates the interaction as moderate. Apixaban and Berotralstat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Berotralstat inhibits P-gp and may increase apixaban exposure. This could raise bleeding risk.
How serious is the interaction between Apixaban and Berotralstat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of bleeding, particularly in patients with renal impairment or low body weight.
What other medicines interact with Apixaban?
MediHelp also lists interactions of Apixaban with, for example, Dabigatran, Defibrotide, Edoxaban. The full list is on the Apixaban page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
