藥物交互作用
Artesunate + Nevirapine
嚴重程度: 中度
Artesunate and Nevirapine: moderate interaction.
最後更新
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摘要
Nevirapine may reduce exposure to dihydroartemisinin, the active metabolite of artesunate, by inducing metabolic enzymes. This may reduce antimalarial efficacy.
用白話說明這項交互作用的意義
Artesunate and Nevirapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Artesunate belongs to Anti Parasitic; Nevirapine belongs to Anti Virals.
為什麼會發生
Nevirapine induces CYP enzymes and UGT-mediated clearance, lowering active artesunate metabolite exposure.
處置方式
Use the full recommended artesunate course and monitor parasitological and clinical response. Consider follow-up testing for recrudescence.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Nevirapine 的其他交互作用
Artesunate 的其他交互作用
常見問題
Can I take Artesunate with Nevirapine?
MediHelp rates the interaction as moderate. Artesunate and Nevirapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nevirapine may reduce exposure to dihydroartemisinin, the active metabolite of artesunate, by inducing metabolic enzymes. This may reduce antimalarial efficacy.
How serious is the interaction between Artesunate and Nevirapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the full recommended artesunate course and monitor parasitological and clinical response. Consider follow-up testing for recrudescence.
What other medicines interact with Nevirapine?
MediHelp also lists interactions of Nevirapine with, for example, Elbasvir / grazoprevir, Ranolazine, St john's wort. The full list is on the Nevirapine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
