藥物交互作用
Atazanavir + Calcium carbonate
嚴重程度: 中度
Atazanavir and Calcium carbonate: moderate interaction.
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摘要
Atazanavir needs an acidic environment to dissolve, and calcium carbonate raises gastric pH. Reduced atazanavir exposure can lead to virologic failure and resistance.
用白話說明這項交互作用的意義
Atazanavir and Calcium carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atazanavir belongs to Anti Virals; Calcium carbonate belongs to Gastrointestinal Tract.
為什麼會發生
Elevated gastric pH decreases the solubility and absorption of atazanavir.
處置方式
Give atazanavir at least 2 hours before or 1 hour after the antacid.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Calcium carbonate 的其他交互作用
Atazanavir 的其他交互作用
常見問題
Can I take Atazanavir with Calcium carbonate?
MediHelp rates the interaction as moderate. Atazanavir and Calcium carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atazanavir needs an acidic environment to dissolve, and calcium carbonate raises gastric pH. Reduced atazanavir exposure can lead to virologic failure and resistance.
How serious is the interaction between Atazanavir and Calcium carbonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give atazanavir at least 2 hours before or 1 hour after the antacid.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
