藥物交互作用
Atorvastatin + Eltrombopag
嚴重程度: 中度
Atorvastatin and Eltrombopag: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Eltrombopag inhibits OATP1B1 and may increase atorvastatin exposure. This raises the risk of statin-related myopathy.
用白話說明這項交互作用的意義
Atorvastatin and Eltrombopag can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atorvastatin belongs to Cardiovascular; Eltrombopag belongs to Miscellaneous.
為什麼會發生
Inhibition of hepatic OATP1B1 uptake raises systemic statin concentrations.
處置方式
Consider a lower atorvastatin dose and monitor for muscle pain, weakness or CK elevation.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Atorvastatin 的其他交互作用
Eltrombopag 的其他交互作用
常見問題
Can I take Atorvastatin with Eltrombopag?
MediHelp rates the interaction as moderate. Atorvastatin and Eltrombopag can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eltrombopag inhibits OATP1B1 and may increase atorvastatin exposure. This raises the risk of statin-related myopathy.
How serious is the interaction between Atorvastatin and Eltrombopag?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider a lower atorvastatin dose and monitor for muscle pain, weakness or CK elevation.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
