藥物交互作用
Atorvastatin + Roxadustat
嚴重程度: 中度
Atorvastatin and Roxadustat: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Roxadustat raises atorvastatin exposure, which may increase statin-related adverse effects including myopathy and liver enzyme elevation.
用白話說明這項交互作用的意義
Atorvastatin and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atorvastatin belongs to Cardiovascular; Roxadustat belongs to Miscellaneous.
為什麼會發生
Roxadustat inhibits OATP1B1 and BCRP, decreasing hepatic uptake and efflux of atorvastatin.
處置方式
Monitor for muscle symptoms and liver enzymes. Consider reducing the atorvastatin dose.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Roxadustat 的其他交互作用
Atorvastatin 的其他交互作用
常見問題
Can I take Atorvastatin with Roxadustat?
MediHelp rates the interaction as moderate. Atorvastatin and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Roxadustat raises atorvastatin exposure, which may increase statin-related adverse effects including myopathy and liver enzyme elevation.
How serious is the interaction between Atorvastatin and Roxadustat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for muscle symptoms and liver enzymes. Consider reducing the atorvastatin dose.
What other medicines interact with Roxadustat?
MediHelp also lists interactions of Roxadustat with, for example, Gemfibrozil, Probenecid, Calcium acetate. The full list is on the Roxadustat page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
