藥物交互作用
Magnesium + Roxadustat
嚴重程度: 中度
Magnesium and Roxadustat: moderate interaction.
最後更新
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摘要
Magnesium-containing products can bind roxadustat in the gut and reduce how much is absorbed. Lower exposure may blunt the haemoglobin response to treatment.
用白話說明這項交互作用的意義
Magnesium and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Magnesium belongs to Gastrointestinal Tract; Roxadustat belongs to Miscellaneous.
為什麼會發生
Chelation of roxadustat by multivalent cations in the gastrointestinal tract reduces its absorption.
處置方式
Give roxadustat at least 1 hour after magnesium-containing products. Monitor haemoglobin and adjust roxadustat dose if the response is inadequate.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Roxadustat 的其他交互作用
Magnesium 的其他交互作用
常見問題
Can I take Magnesium with Roxadustat?
MediHelp rates the interaction as moderate. Magnesium and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium-containing products can bind roxadustat in the gut and reduce how much is absorbed. Lower exposure may blunt the haemoglobin response to treatment.
How serious is the interaction between Magnesium and Roxadustat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give roxadustat at least 1 hour after magnesium-containing products. Monitor haemoglobin and adjust roxadustat dose if the response is inadequate.
What other medicines interact with Roxadustat?
MediHelp also lists interactions of Roxadustat with, for example, Gemfibrozil, Probenecid, Atorvastatin. The full list is on the Roxadustat page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
