藥物交互作用
Azacitidine + Hydroxyurea
嚴重程度: 中度
Azacitidine and Hydroxyurea: moderate interaction.
最後更新
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摘要
Both agents suppress bone marrow function. Used together they can deepen neutropenia, anemia and thrombocytopenia, raising the risk of infection and bleeding.
用白話說明這項交互作用的意義
Azacitidine and Hydroxyurea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azacitidine belongs to Oncology; Hydroxyurea belongs to Miscellaneous.
為什麼會發生
Additive myelosuppression from two cytotoxic agents.
處置方式
Monitor complete blood counts regularly and adjust doses or delay cycles for significant cytopenias. Provide supportive care as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Hydroxyurea 的其他交互作用
Azacitidine 的其他交互作用
常見問題
Can I take Azacitidine with Hydroxyurea?
MediHelp rates the interaction as moderate. Azacitidine and Hydroxyurea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents suppress bone marrow function. Used together they can deepen neutropenia, anemia and thrombocytopenia, raising the risk of infection and bleeding.
How serious is the interaction between Azacitidine and Hydroxyurea?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts regularly and adjust doses or delay cycles for significant cytopenias. Provide supportive care as needed.
What other medicines interact with Hydroxyurea?
MediHelp also lists interactions of Hydroxyurea with, for example, Didanosine, Adenovirus types 4 and 7 live, Axicabtagene ciloleucel. The full list is on the Hydroxyurea page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
