藥物交互作用
Azacitidine + Trastuzumab
嚴重程度: 中度
Azacitidine and Trastuzumab: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Azacitidine is myelosuppressive, and trastuzumab has been associated with higher rates of neutropenia and febrile neutropenia when combined with myelosuppressive chemotherapy. The combination may increase infection risk.
用白話說明這項交互作用的意義
Azacitidine and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azacitidine belongs to Oncology; Trastuzumab belongs to Oncology.
為什麼會發生
Additive hematologic toxicity; trastuzumab may worsen chemotherapy-induced neutropenia by an incompletely understood mechanism.
處置方式
Monitor complete blood counts regularly and watch for fever or infection; manage neutropenia per standard protocols.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Trastuzumab 的其他交互作用
Azacitidine 的其他交互作用
常見問題
Can I take Azacitidine with Trastuzumab?
MediHelp rates the interaction as moderate. Azacitidine and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azacitidine is myelosuppressive, and trastuzumab has been associated with higher rates of neutropenia and febrile neutropenia when combined with myelosuppressive chemotherapy. The combination may increase infection risk.
How serious is the interaction between Azacitidine and Trastuzumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts regularly and watch for fever or infection; manage neutropenia per standard protocols.
What other medicines interact with Trastuzumab?
MediHelp also lists interactions of Trastuzumab with, for example, Daunorubicin, Doxorubicin liposomal, Doxorubicin. The full list is on the Trastuzumab page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
