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藥物交互作用

Balsalazide + Measles mumps rubella and varicella vaccine live

嚴重程度: 嚴重

Balsalazide and Measles mumps rubella and varicella vaccine live: major interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Balsalazide releases mesalamine, a salicylate, and salicylate use after varicella-containing live vaccines has been linked to Reye's syndrome in children. The risk is theoretical for balsalazide given its low systemic salicylate exposure, but it is a labeled caution.

用白話說明這項交互作用的意義

Balsalazide and Measles mumps rubella and varicella vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

證據等級: Low

為什麼會發生

Salicylate exposure after live varicella virus vaccination is thought to predispose to Reye's syndrome; the precise mechanism is not established.

處置方式

Avoid salicylate-containing products, including balsalazide, for about 6 weeks after vaccination in children and adolescents where possible. If balsalazide is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.

可向藥師詢問的問題

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Balsalazide with Measles mumps rubella and varicella vaccine live?

MediHelp rates the interaction as major. Balsalazide and Measles mumps rubella and varicella vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Balsalazide releases mesalamine, a salicylate, and salicylate use after varicella-containing live vaccines has been linked to Reye's syndrome in children. The risk is theoretical for balsalazide given its low systemic salicylate exposure, but it is a labeled caution.

How serious is the interaction between Balsalazide and Measles mumps rubella and varicella vaccine live?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid salicylate-containing products, including balsalazide, for about 6 weeks after vaccination in children and adolescents where possible. If balsalazide is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.

What other medicines interact with Balsalazide?

MediHelp also lists interactions of Balsalazide with, for example, Varicella virus vaccine live, Aceclofenac, Celecoxib. The full list is on the Balsalazide page.

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