藥物交互作用
Balsalazide + Varicella virus vaccine live
嚴重程度: 嚴重
Balsalazide and Varicella virus vaccine live: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Balsalazide is converted to mesalamine, a salicylate, and salicylate use after live varicella vaccination has been linked to Reye's syndrome in children. The risk is largely theoretical given balsalazide's low systemic salicylate exposure, but it is a labeled caution.
用白話說明這項交互作用的意義
Balsalazide and Varicella virus vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Salicylate exposure after live varicella virus vaccination is thought to predispose to Reye's syndrome; the precise mechanism is not established.
處置方式
Avoid salicylate-containing products, including balsalazide, for about 6 weeks after vaccination in children and adolescents where possible. If balsalazide is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Balsalazide 的其他交互作用
常見問題
Can I take Balsalazide with Varicella virus vaccine live?
MediHelp rates the interaction as major. Balsalazide and Varicella virus vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Balsalazide is converted to mesalamine, a salicylate, and salicylate use after live varicella vaccination has been linked to Reye's syndrome in children. The risk is largely theoretical given balsalazide's low systemic salicylate exposure, but it is a labeled caution.
How serious is the interaction between Balsalazide and Varicella virus vaccine live?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid salicylate-containing products, including balsalazide, for about 6 weeks after vaccination in children and adolescents where possible. If balsalazide is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Aceclofenac, Celecoxib. The full list is on the Balsalazide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
