藥物交互作用
Balsalazide + Mesalamine
嚴重程度: 中度
Balsalazide and Mesalamine: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Balsalazide is a prodrug of mesalamine, so the two are the same active moiety and using both is therapeutic duplication. Combined use would increase mesalamine exposure and the risk of adverse effects such as renal impairment and mesalamine intolerance.
用白話說明這項交互作用的意義
Balsalazide and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Balsalazide belongs to Gastrointestinal Tract; Mesalamine belongs to Gastrointestinal Tract.
為什麼會發生
Duplicate therapy: balsalazide is converted to mesalamine, giving additive exposure to the same active drug.
處置方式
Avoid routine co-prescription; if combined for refractory disease, monitor renal function and watch for mesalamine adverse effects.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Balsalazide 的其他交互作用
Mesalamine 的其他交互作用
常見問題
Can I take Balsalazide with Mesalamine?
MediHelp rates the interaction as moderate. Balsalazide and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Balsalazide is a prodrug of mesalamine, so the two are the same active moiety and using both is therapeutic duplication. Combined use would increase mesalamine exposure and the risk of adverse effects such as renal impairment and mesalamine intolerance.
How serious is the interaction between Balsalazide and Mesalamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine co-prescription; if combined for refractory disease, monitor renal function and watch for mesalamine adverse effects.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
