藥物交互作用
Balsalazide + Voclosporin
嚴重程度: 中度
Balsalazide and Voclosporin: moderate interaction.
最後更新
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摘要
Voclosporin is a calcineurin inhibitor that is nephrotoxic. Mesalamine-type drugs such as balsalazide have rarely been associated with interstitial nephritis and renal impairment, so the renal risk may be additive.
用白話說明這項交互作用的意義
Balsalazide and Voclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Balsalazide belongs to Gastrointestinal Tract; Voclosporin belongs to Miscellaneous.
為什麼會發生
Additive nephrotoxic potential through different mechanisms (calcineurin inhibitor hemodynamic effect and mesalamine interstitial nephritis).
處置方式
Monitor serum creatinine and eGFR at baseline and regularly during combined use. Reduce the voclosporin dose or stop the agents if renal function declines.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Balsalazide 的其他交互作用
Voclosporin 的其他交互作用
常見問題
Can I take Balsalazide with Voclosporin?
MediHelp rates the interaction as moderate. Balsalazide and Voclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Voclosporin is a calcineurin inhibitor that is nephrotoxic. Mesalamine-type drugs such as balsalazide have rarely been associated with interstitial nephritis and renal impairment, so the renal risk may be additive.
How serious is the interaction between Balsalazide and Voclosporin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and eGFR at baseline and regularly during combined use. Reduce the voclosporin dose or stop the agents if renal function declines.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
