藥物交互作用
Balsalazide + Celecoxib
嚴重程度: 中度
Balsalazide and Celecoxib: moderate interaction.
最後更新
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摘要
Balsalazide releases mesalamine in the colon, and celecoxib is an NSAID with renal effects. Concurrent use may add to the risk of renal impairment, especially with dehydration or pre-existing kidney disease. NSAIDs may also aggravate inflammatory bowel disease in some patients.
用白話說明這項交互作用的意義
Balsalazide and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Balsalazide belongs to Gastrointestinal Tract; Celecoxib belongs to Musculoskeletal.
為什麼會發生
Additive nephrotoxic potential from NSAID-mediated prostaglandin inhibition and rare mesalamine-related interstitial nephritis.
處置方式
Monitor renal function periodically and watch for worsening bowel symptoms. Avoid long-term NSAID use where an alternative analgesic is suitable.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Balsalazide 的其他交互作用
Celecoxib 的其他交互作用
常見問題
Can I take Balsalazide with Celecoxib?
MediHelp rates the interaction as moderate. Balsalazide and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Balsalazide releases mesalamine in the colon, and celecoxib is an NSAID with renal effects. Concurrent use may add to the risk of renal impairment, especially with dehydration or pre-existing kidney disease. NSAIDs may also aggravate inflammatory bowel disease in some patients.
How serious is the interaction between Balsalazide and Celecoxib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function periodically and watch for worsening bowel symptoms. Avoid long-term NSAID use where an alternative analgesic is suitable.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
