藥物交互作用
Betrixaban + Ticlopidine
嚴重程度: 嚴重
Betrixaban and Ticlopidine: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Combining an antiplatelet with a factor Xa inhibitor increases the risk of clinically important bleeding. Ticlopidine also carries its own hematologic toxicity.
用白話說明這項交互作用的意義
Betrixaban and Ticlopidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive pharmacodynamic effects of platelet inhibition and factor Xa inhibition.
處置方式
Avoid the combination unless clearly indicated; if used, monitor for bleeding and check blood counts regularly.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ticlopidine 的其他交互作用
常見問題
Can I take Betrixaban with Ticlopidine?
MediHelp rates the interaction as major. Betrixaban and Ticlopidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Combining an antiplatelet with a factor Xa inhibitor increases the risk of clinically important bleeding. Ticlopidine also carries its own hematologic toxicity.
How serious is the interaction between Betrixaban and Ticlopidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination unless clearly indicated; if used, monitor for bleeding and check blood counts regularly.
What other medicines interact with Ticlopidine?
MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Abrocitinib, Acetylsalicylic acid. The full list is on the Ticlopidine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。