藥物交互作用
Bumetanide + Magnesium
嚴重程度: 中度
Bumetanide and Magnesium: moderate interaction.
最後更新
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摘要
Loop diuretics increase urinary magnesium excretion and can cause hypomagnesemia, particularly with long-term use. Low magnesium can worsen arrhythmia risk and potassium depletion.
用白話說明這項交互作用的意義
Bumetanide and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bumetanide belongs to Cardiovascular; Magnesium belongs to Gastrointestinal Tract.
為什麼會發生
Inhibition of the Na-K-2Cl cotransporter in the thick ascending limb reduces paracellular magnesium reabsorption.
處置方式
Monitor serum magnesium and potassium periodically. Supplement magnesium when levels are low.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium 的其他交互作用
Bumetanide 的其他交互作用
常見問題
Can I take Bumetanide with Magnesium?
MediHelp rates the interaction as moderate. Bumetanide and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Loop diuretics increase urinary magnesium excretion and can cause hypomagnesemia, particularly with long-term use. Low magnesium can worsen arrhythmia risk and potassium depletion.
How serious is the interaction between Bumetanide and Magnesium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium and potassium periodically. Supplement magnesium when levels are low.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
