藥物交互作用
Magnesium + Vecuronium
嚴重程度: 嚴重
Magnesium and Vecuronium: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Parenteral magnesium sulfate potentiates vecuronium, leading to faster onset and prolonged neuromuscular blockade. Residual paralysis and respiratory compromise may result.
用白話說明這項交互作用的意義
Magnesium and Vecuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Magnesium belongs to Gastrointestinal Tract; Vecuronium belongs to Musculoskeletal.
為什麼會發生
Magnesium reduces presynaptic acetylcholine release and postsynaptic sensitivity, adding to nondepolarizing blockade.
處置方式
Reduce the vecuronium dose and use train-of-four monitoring. Verify full reversal before extubation.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Magnesium 的其他交互作用
Vecuronium 的其他交互作用
常見問題
Can I take Magnesium with Vecuronium?
MediHelp rates the interaction as major. Magnesium and Vecuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Parenteral magnesium sulfate potentiates vecuronium, leading to faster onset and prolonged neuromuscular blockade. Residual paralysis and respiratory compromise may result.
How serious is the interaction between Magnesium and Vecuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reduce the vecuronium dose and use train-of-four monitoring. Verify full reversal before extubation.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
