藥物交互作用
Amikacin + Magnesium
嚴重程度: 中度
Amikacin and Magnesium: moderate interaction.
最後更新
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摘要
Aminoglycosides cause renal magnesium wasting, which can lead to hypomagnesemia with prolonged therapy. Low magnesium may then compound electrolyte disturbances such as hypokalemia and hypocalcemia.
用白話說明這項交互作用的意義
Amikacin and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amikacin belongs to Anti Bacterial; Magnesium belongs to Gastrointestinal Tract.
為什麼會發生
Aminoglycoside tubular toxicity impairs renal magnesium reabsorption, increasing urinary loss.
處置方式
Monitor serum magnesium, potassium and calcium during prolonged aminoglycoside courses. Replace magnesium as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium 的其他交互作用
Amikacin 的其他交互作用
常見問題
Can I take Amikacin with Magnesium?
MediHelp rates the interaction as moderate. Amikacin and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aminoglycosides cause renal magnesium wasting, which can lead to hypomagnesemia with prolonged therapy. Low magnesium may then compound electrolyte disturbances such as hypokalemia and hypocalcemia.
How serious is the interaction between Amikacin and Magnesium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium, potassium and calcium during prolonged aminoglycoside courses. Replace magnesium as needed.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
