藥物交互作用
Calcifediol + Cholestyramine
嚴重程度: 中度
Calcifediol and Cholestyramine: moderate interaction.
最後更新
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摘要
Cholestyramine can bind fat-soluble vitamin D compounds and reduce bile acid-dependent absorption of calcifediol. This can lower vitamin D status and affect calcium and PTH control.
用白話說明這項交互作用的意義
Calcifediol and Cholestyramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcifediol belongs to Musculoskeletal; Cholestyramine belongs to Cardiovascular.
為什麼會發生
Binding in the gut and interference with bile acid-dependent absorption of the fat-soluble vitamin.
處置方式
Separate calcifediol from cholestyramine by several hours and monitor 25-hydroxyvitamin D, PTH and calcium, adjusting the dose when cholestyramine is started or stopped.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cholestyramine 的其他交互作用
Calcifediol 的其他交互作用
常見問題
Can I take Calcifediol with Cholestyramine?
MediHelp rates the interaction as moderate. Calcifediol and Cholestyramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cholestyramine can bind fat-soluble vitamin D compounds and reduce bile acid-dependent absorption of calcifediol. This can lower vitamin D status and affect calcium and PTH control.
How serious is the interaction between Calcifediol and Cholestyramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate calcifediol from cholestyramine by several hours and monitor 25-hydroxyvitamin D, PTH and calcium, adjusting the dose when cholestyramine is started or stopped.
What other medicines interact with Cholestyramine?
MediHelp also lists interactions of Cholestyramine with, for example, Cholic acid, Deferasirox, Leflunomide. The full list is on the Cholestyramine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
