藥物交互作用
Canagliflozin + Somatropin
嚴重程度: 中度
Canagliflozin and Somatropin: moderate interaction.
最後更新
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摘要
Somatropin can reduce insulin sensitivity and raise blood glucose, which may partly counteract the glucose-lowering effect of canagliflozin. Glycemic control can worsen after growth hormone is started or the dose is increased.
用白話說明這項交互作用的意義
Canagliflozin and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Canagliflozin belongs to Endocrine; Somatropin belongs to Endocrine.
為什麼會發生
Pharmacodynamic antagonism: growth hormone induces insulin resistance and increases hepatic glucose output and lipolysis.
處置方式
Monitor blood glucose and HbA1c when starting or adjusting somatropin. Increase the antidiabetic dose if needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Somatropin 的其他交互作用
Canagliflozin 的其他交互作用
常見問題
Can I take Canagliflozin with Somatropin?
MediHelp rates the interaction as moderate. Canagliflozin and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Somatropin can reduce insulin sensitivity and raise blood glucose, which may partly counteract the glucose-lowering effect of canagliflozin. Glycemic control can worsen after growth hormone is started or the dose is increased.
How serious is the interaction between Canagliflozin and Somatropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c when starting or adjusting somatropin. Increase the antidiabetic dose if needed.
What other medicines interact with Somatropin?
MediHelp also lists interactions of Somatropin with, for example, Acarbose, Albiglutide, Alogliptin-metformin. The full list is on the Somatropin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。