藥物交互作用
Carbamazepine + Levonorgestrel
嚴重程度: 嚴重
Carbamazepine and Levonorgestrel: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Carbamazepine lowers levonorgestrel exposure and can cause contraceptive failure, including with emergency contraception. Unintended pregnancy is the main concern.
用白話說明這項交互作用的意義
Carbamazepine and Levonorgestrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Carbamazepine belongs to Central Nervous System; Levonorgestrel belongs to Endocrine.
為什麼會發生
Carbamazepine induces CYP3A4 and increases the metabolism of levonorgestrel.
處置方式
Use a non-hormonal contraceptive method such as a copper IUD, or add a barrier method. For emergency contraception, consider a copper IUD or follow label advice for an increased dose.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Carbamazepine 的其他交互作用
Levonorgestrel 的其他交互作用
常見問題
Can I take Carbamazepine with Levonorgestrel?
MediHelp rates the interaction as major. Carbamazepine and Levonorgestrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Carbamazepine lowers levonorgestrel exposure and can cause contraceptive failure, including with emergency contraception. Unintended pregnancy is the main concern.
How serious is the interaction between Carbamazepine and Levonorgestrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use a non-hormonal contraceptive method such as a copper IUD, or add a barrier method. For emergency contraception, consider a copper IUD or follow label advice for an increased dose.
What other medicines interact with Carbamazepine?
MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
