藥物交互作用
Cefazolin + Streptomycin
嚴重程度: 中度
Cefazolin and Streptomycin: moderate interaction.
最後更新
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摘要
Combining cefazolin with streptomycin may increase the chance of renal injury, particularly in patients with reduced kidney function or dehydration. Streptomycin itself carries vestibular and cochlear toxicity, so any added renal impairment can raise drug exposure and worsen ototoxicity.
用白話說明這項交互作用的意義
Cefazolin and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefazolin belongs to Anti Bacterial; Streptomycin belongs to Anti Bacterial.
為什麼會發生
Additive nephrotoxic potential; reduced renal clearance of streptomycin can increase its toxicity.
處置方式
Monitor renal function and streptomycin levels, and assess hearing and balance during therapy. Adjust the streptomycin dose for renal function.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefazolin 的其他交互作用
Streptomycin 的其他交互作用
常見問題
Can I take Cefazolin with Streptomycin?
MediHelp rates the interaction as moderate. Cefazolin and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining cefazolin with streptomycin may increase the chance of renal injury, particularly in patients with reduced kidney function or dehydration. Streptomycin itself carries vestibular and cochlear toxicity, so any added renal impairment can raise drug exposure and worsen ototoxicity.
How serious is the interaction between Cefazolin and Streptomycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and streptomycin levels, and assess hearing and balance during therapy. Adjust the streptomycin dose for renal function.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefazolin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
