藥物交互作用
Cefpodoxime + Esomeprazole
嚴重程度: 中度
Cefpodoxime and Esomeprazole: moderate interaction.
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摘要
Cefpodoxime proxetil needs gastric acid for dissolution and absorption. Acid suppression reduces its bioavailability, which may lead to treatment failure.
用白話說明這項交互作用的意義
Cefpodoxime and Esomeprazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefpodoxime belongs to Anti Bacterial; Esomeprazole belongs to Gastrointestinal Tract.
為什麼會發生
Higher gastric pH reduces the dissolution and absorption of cefpodoxime proxetil.
處置方式
Avoid the combination if possible and choose an antibiotic that is not acid-dependent. If used, give cefpodoxime with food and monitor the clinical response.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Esomeprazole 的其他交互作用
Cefpodoxime 的其他交互作用
常見問題
Can I take Cefpodoxime with Esomeprazole?
MediHelp rates the interaction as moderate. Cefpodoxime and Esomeprazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefpodoxime proxetil needs gastric acid for dissolution and absorption. Acid suppression reduces its bioavailability, which may lead to treatment failure.
How serious is the interaction between Cefpodoxime and Esomeprazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if possible and choose an antibiotic that is not acid-dependent. If used, give cefpodoxime with food and monitor the clinical response.
What other medicines interact with Esomeprazole?
MediHelp also lists interactions of Esomeprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Esomeprazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
