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藥物交互作用

Cholestyramine + Ergocalciferol

嚴重程度: 中度

Cholestyramine and Ergocalciferol: moderate interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Cholestyramine binds bile acids and impairs absorption of fat-soluble vitamins including vitamin D. Long-term use may lead to lower vitamin D status.

用白話說明這項交互作用的意義

Cholestyramine and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cholestyramine belongs to Cardiovascular; Ergocalciferol belongs to Musculoskeletal.

證據等級: Moderate

為什麼會發生

Bile acid sequestration reduces micelle formation and intestinal absorption of vitamin D.

處置方式

Give vitamin D at least 4 hours before cholestyramine. Monitor 25-hydroxyvitamin D levels in long-term users.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Cholestyramine 與 Ergocalciferol 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Cholestyramine with Ergocalciferol?

MediHelp rates the interaction as moderate. Cholestyramine and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cholestyramine binds bile acids and impairs absorption of fat-soluble vitamins including vitamin D. Long-term use may lead to lower vitamin D status.

How serious is the interaction between Cholestyramine and Ergocalciferol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give vitamin D at least 4 hours before cholestyramine. Monitor 25-hydroxyvitamin D levels in long-term users.

What other medicines interact with Ergocalciferol?

MediHelp also lists interactions of Ergocalciferol with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Ergocalciferol page.

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