藥物交互作用
Cholestyramine + Oxytetracycline
嚴重程度: 中度
Cholestyramine and Oxytetracycline: moderate interaction.
最後更新
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摘要
Cholestyramine binds tetracyclines in the gut and reduces their absorption, risking subtherapeutic antibiotic levels and treatment failure.
用白話說明這項交互作用的意義
Cholestyramine and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cholestyramine belongs to Cardiovascular; Oxytetracycline belongs to Anti Bacterial.
為什麼會發生
Resin binds oxytetracycline in the gut lumen, decreasing absorption.
處置方式
Give oxytetracycline at least 2 hours before or 4 to 6 hours after cholestyramine. Monitor clinical response to the antibiotic.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cholestyramine 的其他交互作用
Oxytetracycline 的其他交互作用
常見問題
Can I take Cholestyramine with Oxytetracycline?
MediHelp rates the interaction as moderate. Cholestyramine and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cholestyramine binds tetracyclines in the gut and reduces their absorption, risking subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Cholestyramine and Oxytetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oxytetracycline at least 2 hours before or 4 to 6 hours after cholestyramine. Monitor clinical response to the antibiotic.
What other medicines interact with Cholestyramine?
MediHelp also lists interactions of Cholestyramine with, for example, Cholic acid, Deferasirox, Leflunomide. The full list is on the Cholestyramine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。