藥物交互作用
Eletriptan + Tipranavir
嚴重程度: 禁忌併用
Eletriptan and Tipranavir: contraindicated interaction.
最後更新
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摘要
Tipranavir, given with ritonavir, strongly inhibits CYP3A4 and can substantially increase eletriptan concentrations. This raises the risk of excessive vasoconstriction and cardiovascular events.
用白話說明這項交互作用的意義
Eletriptan and Tipranavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Eletriptan belongs to Central Nervous System; Tipranavir belongs to Anti Virals.
為什麼會發生
Inhibition of CYP3A4 metabolism of eletriptan, with ritonavir-boosting enhancing the effect.
處置方式
Avoid eletriptan within 72 hours of tipranavir/ritonavir. Use an alternative acute migraine therapy with less CYP3A4 dependence.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Eletriptan 的其他交互作用
Tipranavir 的其他交互作用
常見問題
Can I take Eletriptan with Tipranavir?
MediHelp rates the interaction as contraindicated. Eletriptan and Tipranavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Tipranavir, given with ritonavir, strongly inhibits CYP3A4 and can substantially increase eletriptan concentrations. This raises the risk of excessive vasoconstriction and cardiovascular events.
How serious is the interaction between Eletriptan and Tipranavir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid eletriptan within 72 hours of tipranavir/ritonavir. Use an alternative acute migraine therapy with less CYP3A4 dependence.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
