藥物交互作用
Esketamine + Rufinamide
嚴重程度: 中度
Esketamine and Rufinamide: moderate interaction.
最後更新
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摘要
Rufinamide commonly causes somnolence and dizziness, which can add to esketamine's sedative and dissociative effects. The result may be greater drowsiness and impaired coordination after dosing.
用白話說明這項交互作用的意義
Esketamine and Rufinamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Esketamine belongs to Central Nervous System; Rufinamide belongs to Central Nervous System.
為什麼會發生
Additive CNS depressant adverse effects; no established pharmacokinetic interaction.
處置方式
Observe for sedation and dizziness during the post-dose period and counsel the patient about driving and hazardous activity.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Esketamine 的其他交互作用
Rufinamide 的其他交互作用
常見問題
Can I take Esketamine with Rufinamide?
MediHelp rates the interaction as moderate. Esketamine and Rufinamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rufinamide commonly causes somnolence and dizziness, which can add to esketamine's sedative and dissociative effects. The result may be greater drowsiness and impaired coordination after dosing.
How serious is the interaction between Esketamine and Rufinamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Observe for sedation and dizziness during the post-dose period and counsel the patient about driving and hazardous activity.
What other medicines interact with Esketamine?
MediHelp also lists interactions of Esketamine with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Esketamine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
