藥物交互作用
Etonogestrel + Lesinurad
嚴重程度: 中度
Etonogestrel and Lesinurad: moderate interaction.
最後更新
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摘要
Lesinurad is a weak CYP3A inducer and may lower exposure to hormonal contraceptives metabolized by CYP3A4. This could reduce contraceptive efficacy and risk unintended pregnancy.
用白話說明這項交互作用的意義
Etonogestrel and Lesinurad can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Etonogestrel belongs to Endocrine; Lesinurad belongs to Genitourinary.
為什麼會發生
Weak induction of CYP3A4 by lesinurad increases metabolism of the progestin.
處置方式
Advise an additional nonhormonal contraceptive method while lesinurad is used. Note that lesinurad has been discontinued in many markets.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Lesinurad 的其他交互作用
Etonogestrel 的其他交互作用
常見問題
Can I take Etonogestrel with Lesinurad?
MediHelp rates the interaction as moderate. Etonogestrel and Lesinurad can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lesinurad is a weak CYP3A inducer and may lower exposure to hormonal contraceptives metabolized by CYP3A4. This could reduce contraceptive efficacy and risk unintended pregnancy.
How serious is the interaction between Etonogestrel and Lesinurad?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise an additional nonhormonal contraceptive method while lesinurad is used. Note that lesinurad has been discontinued in many markets.
What other medicines interact with Lesinurad?
MediHelp also lists interactions of Lesinurad with, for example, Norethisterone, Acetylsalicylic acid, Amiodarone. The full list is on the Lesinurad page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
