藥物交互作用
Flecainide + Pimozide
嚴重程度: 禁忌併用
Flecainide and Pimozide: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Pimozide markedly prolongs the QT interval and carries a risk of torsades de pointes, and flecainide adds proarrhythmic effects. The combination can cause life-threatening ventricular arrhythmias.
用白話說明這項交互作用的意義
Flecainide and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Flecainide belongs to Cardiovascular; Pimozide belongs to Central Nervous System.
為什麼會發生
Additive effects on cardiac repolarization and conduction.
處置方式
Do not use together; choose an alternative antipsychotic or antiarrhythmic with no QT effect.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Flecainide 的其他交互作用
Pimozide 的其他交互作用
常見問題
Can I take Flecainide with Pimozide?
MediHelp rates the interaction as contraindicated. Flecainide and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Pimozide markedly prolongs the QT interval and carries a risk of torsades de pointes, and flecainide adds proarrhythmic effects. The combination can cause life-threatening ventricular arrhythmias.
How serious is the interaction between Flecainide and Pimozide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose an alternative antipsychotic or antiarrhythmic with no QT effect.
What other medicines interact with Flecainide?
MediHelp also lists interactions of Flecainide with, for example, Nirmatrelvir, Nirmatrelvir / ritonavir, Ritonavir. The full list is on the Flecainide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
