藥物交互作用
Flecainide + Vandetanib
嚴重程度: 禁忌併用
Flecainide and Vandetanib: contraindicated interaction.
最後更新
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摘要
Vandetanib markedly prolongs the QT interval and carries a boxed warning for torsade de pointes and sudden death. Combining it with flecainide further raises the risk of fatal arrhythmias.
用白話說明這項交互作用的意義
Flecainide and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Flecainide belongs to Cardiovascular; Vandetanib belongs to Oncology.
為什麼會發生
Additive effects on cardiac repolarization and conduction.
處置方式
Avoid the combination and use an alternative antiarrhythmic. Vandetanib labeling advises against drugs known to prolong QT.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Flecainide 的其他交互作用
Vandetanib 的其他交互作用
常見問題
Can I take Flecainide with Vandetanib?
MediHelp rates the interaction as contraindicated. Flecainide and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Vandetanib markedly prolongs the QT interval and carries a boxed warning for torsade de pointes and sudden death. Combining it with flecainide further raises the risk of fatal arrhythmias.
How serious is the interaction between Flecainide and Vandetanib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use an alternative antiarrhythmic. Vandetanib labeling advises against drugs known to prolong QT.
What other medicines interact with Flecainide?
MediHelp also lists interactions of Flecainide with, for example, Nirmatrelvir, Nirmatrelvir / ritonavir, Pimozide. The full list is on the Flecainide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
