藥物交互作用
Foscarnet + Zoledronic acid
嚴重程度: 中度
Foscarnet and Zoledronic acid: moderate interaction.
最後更新
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摘要
Both drugs lower serum calcium: zoledronic acid by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may cause symptomatic hypocalcemia, including tetany, paresthesias and seizures or arrhythmias.
用白話說明這項交互作用的意義
Foscarnet and Zoledronic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Foscarnet belongs to Anti Virals; Zoledronic acid belongs to Musculoskeletal.
為什麼會發生
Additive lowering of serum calcium through bone resorption inhibition and chelation of ionized calcium.
處置方式
Check calcium, magnesium and ionized calcium before and during therapy, and correct deficits. Replace calcium and vitamin D as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Zoledronic acid 的其他交互作用
Foscarnet 的其他交互作用
常見問題
Can I take Foscarnet with Zoledronic acid?
MediHelp rates the interaction as moderate. Foscarnet and Zoledronic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower serum calcium: zoledronic acid by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may cause symptomatic hypocalcemia, including tetany, paresthesias and seizures or arrhythmias.
How serious is the interaction between Foscarnet and Zoledronic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check calcium, magnesium and ionized calcium before and during therapy, and correct deficits. Replace calcium and vitamin D as needed.
What other medicines interact with Zoledronic acid?
MediHelp also lists interactions of Zoledronic acid with, for example, Amikacin, Bumetanide, Dichlorphenamide. The full list is on the Zoledronic acid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
