藥物交互作用
Gliclazide + Metreleptin
嚴重程度: 中度
Gliclazide and Metreleptin: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Metreleptin improves insulin sensitivity and lowers glucose, so combining it with a sulfonylurea can cause hypoglycemia. The label advises reducing insulin or secretagogue doses in this setting.
用白話說明這項交互作用的意義
Gliclazide and Metreleptin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Gliclazide belongs to Endocrine; Metreleptin belongs to Endocrine.
為什麼會發生
Additive pharmacodynamic glucose lowering through enhanced insulin sensitivity plus increased insulin secretion.
處置方式
Monitor blood glucose closely when starting metreleptin and reduce the gliclazide dose proactively if glucose falls.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Gliclazide 的其他交互作用
Metreleptin 的其他交互作用
常見問題
Can I take Gliclazide with Metreleptin?
MediHelp rates the interaction as moderate. Gliclazide and Metreleptin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Metreleptin improves insulin sensitivity and lowers glucose, so combining it with a sulfonylurea can cause hypoglycemia. The label advises reducing insulin or secretagogue doses in this setting.
How serious is the interaction between Gliclazide and Metreleptin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely when starting metreleptin and reduce the gliclazide dose proactively if glucose falls.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
