藥物交互作用
Ivacaftor + Micafungin
嚴重程度: 輕微
Ivacaftor and Micafungin: minor interaction.
最後更新
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摘要
Ivacaftor is a sensitive CYP3A4 substrate, and micafungin may weakly inhibit CYP3A4 in vitro. A small increase in ivacaftor exposure is possible but not well documented clinically.
用白話說明這項交互作用的意義
Ivacaftor and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ivacaftor belongs to Miscellaneous; Micafungin belongs to Anti Fungals.
為什麼會發生
Possible weak CYP3A4 inhibition by micafungin reducing ivacaftor metabolism.
處置方式
Dose adjustment is not required for weak inhibitors; monitor for ivacaftor adverse effects such as raised transaminases and headache.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Micafungin 的其他交互作用
Ivacaftor 的其他交互作用
常見問題
Can I take Ivacaftor with Micafungin?
MediHelp rates the interaction as minor. Ivacaftor and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ivacaftor is a sensitive CYP3A4 substrate, and micafungin may weakly inhibit CYP3A4 in vitro. A small increase in ivacaftor exposure is possible but not well documented clinically.
How serious is the interaction between Ivacaftor and Micafungin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Dose adjustment is not required for weak inhibitors; monitor for ivacaftor adverse effects such as raised transaminases and headache.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
