藥物交互作用
Isavuconazonium + Micafungin
嚴重程度: 輕微
Isavuconazonium and Micafungin: minor interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Micafungin is a weak CYP3A4 inhibitor, and isavuconazole is a CYP3A4 substrate, so a small rise in isavuconazole exposure is theoretically possible. This is unlikely to be clinically important, and the two antifungals are sometimes used together.
用白話說明這項交互作用的意義
Isavuconazonium and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Isavuconazonium belongs to Anti Fungals; Micafungin belongs to Anti Fungals.
為什麼會發生
Theoretical weak CYP3A4 inhibition by micafungin reducing isavuconazole clearance.
處置方式
No empirical dose adjustment is needed; monitor for isavuconazole adverse effects such as liver enzyme elevation.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Micafungin 的其他交互作用
Isavuconazonium 的其他交互作用
常見問題
Can I take Isavuconazonium with Micafungin?
MediHelp rates the interaction as minor. Isavuconazonium and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Micafungin is a weak CYP3A4 inhibitor, and isavuconazole is a CYP3A4 substrate, so a small rise in isavuconazole exposure is theoretically possible. This is unlikely to be clinically important, and the two antifungals are sometimes used together.
How serious is the interaction between Isavuconazonium and Micafungin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empirical dose adjustment is needed; monitor for isavuconazole adverse effects such as liver enzyme elevation.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
