藥物交互作用
Lonafarnib + Micafungin
嚴重程度: 輕微
Lonafarnib and Micafungin: minor interaction.
最後更新
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摘要
Lonafarnib is a sensitive CYP3A substrate. Micafungin is at most a weak CYP3A inhibitor, so any increase in lonafarnib exposure would be small.
用白話說明這項交互作用的意義
Lonafarnib and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lonafarnib belongs to Miscellaneous; Micafungin belongs to Anti Fungals.
為什麼會發生
Weak CYP3A4 inhibition by micafungin could slightly reduce lonafarnib clearance.
處置方式
No dose change is generally needed; monitor for lonafarnib adverse effects such as gastrointestinal toxicity and palpitations or syncope.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Micafungin 的其他交互作用
Lonafarnib 的其他交互作用
常見問題
Can I take Lonafarnib with Micafungin?
MediHelp rates the interaction as minor. Lonafarnib and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lonafarnib is a sensitive CYP3A substrate. Micafungin is at most a weak CYP3A inhibitor, so any increase in lonafarnib exposure would be small.
How serious is the interaction between Lonafarnib and Micafungin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is generally needed; monitor for lonafarnib adverse effects such as gastrointestinal toxicity and palpitations or syncope.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
