藥物交互作用
Magnesium citrate + Sodium polystyrene sulfonate
嚴重程度: 中度
Magnesium citrate and Sodium polystyrene sulfonate: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Sodium polystyrene sulfonate binds cations in the gut including magnesium, and can cause hypomagnesemia. Magnesium-containing laxatives may also bind to the resin and, with non-absorbable cation exchangers, have been associated with metabolic alkalosis because the resin's buffering of bicarbonate is reduced.
用白話說明這項交互作用的意義
Magnesium citrate and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Magnesium citrate belongs to Gastrointestinal Tract; Sodium polystyrene sulfonate belongs to Miscellaneous.
為什麼會發生
Cation exchange resin binds magnesium in the gut, and binding of magnesium reduces neutralization of bicarbonate, which can lead to systemic alkalosis.
處置方式
Avoid giving magnesium-containing laxatives or antacids with the resin, and separate other oral drugs by at least 3 hours. Monitor serum electrolytes and acid-base status during therapy.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium citrate 的其他交互作用
Sodium polystyrene sulfonate 的其他交互作用
常見問題
Can I take Magnesium citrate with Sodium polystyrene sulfonate?
MediHelp rates the interaction as moderate. Magnesium citrate and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate binds cations in the gut including magnesium, and can cause hypomagnesemia. Magnesium-containing laxatives may also bind to the resin and, with non-absorbable cation exchangers, have been associated with metabolic alkalosis because the resin's buffering of bicarbonate is reduced.
How serious is the interaction between Magnesium citrate and Sodium polystyrene sulfonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving magnesium-containing laxatives or antacids with the resin, and separate other oral drugs by at least 3 hours. Monitor serum electrolytes and acid-base status during therapy.
What other medicines interact with Magnesium citrate?
MediHelp also lists interactions of Magnesium citrate with, for example, Ciprofloxacin, Baloxavir marboxil, Bictegravir. The full list is on the Magnesium citrate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
