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藥物交互作用

Deflazacort + Sodium polystyrene sulfonate

嚴重程度: 中度

Deflazacort and Sodium polystyrene sulfonate: moderate interaction.

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本頁的臨床內容僅提供英文版。

摘要

Sodium polystyrene sulfonate removes potassium through the gut and corticosteroids increase renal potassium excretion, so hypokalemia may be more pronounced. Sodium load from the resin may also add to corticosteroid-related fluid retention.

用白話說明這項交互作用的意義

Deflazacort and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Deflazacort belongs to Miscellaneous; Sodium polystyrene sulfonate belongs to Miscellaneous.

證據等級: Moderate

為什麼會發生

Additive potassium lowering through cation exchange in the colon and corticosteroid-induced kaliuresis.

處置方式

Monitor serum potassium regularly and stop or reduce the resin when potassium approaches the normal range.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Deflazacort 與 Sodium polystyrene sulfonate 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Deflazacort with Sodium polystyrene sulfonate?

MediHelp rates the interaction as moderate. Deflazacort and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate removes potassium through the gut and corticosteroids increase renal potassium excretion, so hypokalemia may be more pronounced. Sodium load from the resin may also add to corticosteroid-related fluid retention.

How serious is the interaction between Deflazacort and Sodium polystyrene sulfonate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium regularly and stop or reduce the resin when potassium approaches the normal range.

What other medicines interact with Deflazacort?

MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.

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