藥物交互作用
Lithium + Sodium polystyrene sulfonate
嚴重程度: 中度
Lithium and Sodium polystyrene sulfonate: moderate interaction.
最後更新
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摘要
Sodium polystyrene sulfonate is a cation-exchange resin that can bind lithium in the gut and lower its absorption and serum concentration. It is also used to treat lithium overdose, so unintended lithium loss could reduce mood-stabilising effect.
用白話說明這項交互作用的意義
Lithium and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lithium belongs to Central Nervous System; Sodium polystyrene sulfonate belongs to Miscellaneous.
為什麼會發生
Cation-exchange resin binds lithium in the gastrointestinal tract, reducing absorption.
處置方式
Separate doses by at least several hours, giving lithium well before the resin, and monitor serum lithium during prolonged co-therapy.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Lithium 的其他交互作用
Sodium polystyrene sulfonate 的其他交互作用
常見問題
Can I take Lithium with Sodium polystyrene sulfonate?
MediHelp rates the interaction as moderate. Lithium and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate is a cation-exchange resin that can bind lithium in the gut and lower its absorption and serum concentration. It is also used to treat lithium overdose, so unintended lithium loss could reduce mood-stabilising effect.
How serious is the interaction between Lithium and Sodium polystyrene sulfonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least several hours, giving lithium well before the resin, and monitor serum lithium during prolonged co-therapy.
What other medicines interact with Lithium?
MediHelp also lists interactions of Lithium with, for example, Thioridazine, Vandetanib, Aceclofenac. The full list is on the Lithium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
