藥物交互作用
Melatonin + Viloxazine
嚴重程度: 中度
Melatonin and Viloxazine: moderate interaction.
最後更新
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摘要
Viloxazine is a strong CYP1A2 inhibitor and melatonin is cleared mainly via CYP1A2. Melatonin exposure may rise substantially, increasing drowsiness.
用白話說明這項交互作用的意義
Melatonin and Viloxazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Melatonin belongs to Gastrointestinal Tract; Viloxazine belongs to Central Nervous System.
為什麼會發生
Strong CYP1A2 inhibition by viloxazine reduces melatonin clearance.
處置方式
Use a low melatonin dose and monitor for excessive sedation, or avoid melatonin during viloxazine therapy.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Melatonin 的其他交互作用
常見問題
Can I take Melatonin with Viloxazine?
MediHelp rates the interaction as moderate. Melatonin and Viloxazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Viloxazine is a strong CYP1A2 inhibitor and melatonin is cleared mainly via CYP1A2. Melatonin exposure may rise substantially, increasing drowsiness.
How serious is the interaction between Melatonin and Viloxazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use a low melatonin dose and monitor for excessive sedation, or avoid melatonin during viloxazine therapy.
What other medicines interact with Melatonin?
MediHelp also lists interactions of Melatonin with, for example, Fluvoxamine, Alfentanil, Belladonna and opium. The full list is on the Melatonin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
