藥物交互作用
Microbiota + Rifaximin
嚴重程度: 嚴重
Microbiota and Rifaximin: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Oral fecal microbiota contains live bacterial spores intended to restore the gut flora. Rifaximin acts in the gut lumen and can reduce the engrafting organisms, lowering efficacy. Antibiotic courses should end before the microbiota product is given.
用白話說明這項交互作用的意義
Microbiota and Rifaximin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Luminal antibacterial activity of rifaximin suppresses the administered live bacterial spores and impairs engraftment.
處置方式
Finish the antibiotic course and allow the interval in the product labeling before giving microbiota. Avoid concurrent rifaximin unless essential.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Rifaximin 的其他交互作用
常見問題
Can I take Microbiota with Rifaximin?
MediHelp rates the interaction as major. Microbiota and Rifaximin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral fecal microbiota contains live bacterial spores intended to restore the gut flora. Rifaximin acts in the gut lumen and can reduce the engrafting organisms, lowering efficacy. Antibiotic courses should end before the microbiota product is given.
How serious is the interaction between Microbiota and Rifaximin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish the antibiotic course and allow the interval in the product labeling before giving microbiota. Avoid concurrent rifaximin unless essential.
What other medicines interact with Rifaximin?
MediHelp also lists interactions of Rifaximin with, for example, Cholera vaccine, Amiodarone, Bcg intravesical live. The full list is on the Rifaximin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
