藥物交互作用
Orlistat + Vitamin k1
嚴重程度: 中度
Orlistat and Vitamin k1: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Orlistat decreases absorption of fat-soluble vitamins including vitamin K, and reduced vitamin K status may occur with prolonged use. This matters most for patients taking warfarin, in whom INR may rise.
用白話說明這項交互作用的意義
Orlistat and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Orlistat belongs to Miscellaneous; Vitamin k1 belongs to Cardiovascular.
為什麼會發生
Inhibition of gastrointestinal lipase reduces absorption of fat-soluble vitamins.
處置方式
Take vitamin K-containing supplements at least 2 hours apart from orlistat. Monitor INR in patients on vitamin K antagonists.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Orlistat 的其他交互作用
Vitamin k1 的其他交互作用
常見問題
Can I take Orlistat with Vitamin k1?
MediHelp rates the interaction as moderate. Orlistat and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Orlistat decreases absorption of fat-soluble vitamins including vitamin K, and reduced vitamin K status may occur with prolonged use. This matters most for patients taking warfarin, in whom INR may rise.
How serious is the interaction between Orlistat and Vitamin k1?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take vitamin K-containing supplements at least 2 hours apart from orlistat. Monitor INR in patients on vitamin K antagonists.
What other medicines interact with Orlistat?
MediHelp also lists interactions of Orlistat with, for example, Cyclosporine, Cyclosporin, Triheptanoin. The full list is on the Orlistat page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
