藥物交互作用
Colestipol + Vitamin k1
嚴重程度: 中度
Colestipol and Vitamin k1: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Colestipol is a bile acid sequestrant that impairs absorption of fat-soluble vitamins, including vitamin K. Prolonged use may lower vitamin K status and, in susceptible patients, contribute to prolonged clotting times or bleeding.
用白話說明這項交互作用的意義
Colestipol and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colestipol belongs to Cardiovascular; Vitamin k1 belongs to Cardiovascular.
為什麼會發生
Colestipol binds bile acids in the gut, reducing micelle formation and absorption of oral vitamin K.
處置方式
Give oral vitamin K at least 4 hours before or after colestipol. Monitor INR or prothrombin time in patients on long-term colestipol or with other risk factors for deficiency.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Vitamin k1 的其他交互作用
Colestipol 的其他交互作用
常見問題
Can I take Colestipol with Vitamin k1?
MediHelp rates the interaction as moderate. Colestipol and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol is a bile acid sequestrant that impairs absorption of fat-soluble vitamins, including vitamin K. Prolonged use may lower vitamin K status and, in susceptible patients, contribute to prolonged clotting times or bleeding.
How serious is the interaction between Colestipol and Vitamin k1?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral vitamin K at least 4 hours before or after colestipol. Monitor INR or prothrombin time in patients on long-term colestipol or with other risk factors for deficiency.
What other medicines interact with Vitamin k1?
MediHelp also lists interactions of Vitamin k1 with, for example, Warfarin, Cholestyramine, Ketorolac intranasal. The full list is on the Vitamin k1 page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
