藥物交互作用
Mirtazapine + Pimozide
嚴重程度: 禁忌併用
Mirtazapine and Pimozide: contraindicated interaction.
最後更新
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摘要
Pimozide prolongs the QT interval and can cause torsades de pointes, and mirtazapine may contribute additional QT prolongation. Together they raise the risk of serious ventricular arrhythmia.
用白話說明這項交互作用的意義
Mirtazapine and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Mirtazapine belongs to Central Nervous System; Pimozide belongs to Central Nervous System.
為什麼會發生
Additive QTc prolongation through delayed cardiac repolarization.
處置方式
Avoid the combination and select an antidepressant with minimal QT effect if pimozide is required. Check baseline ECG and electrolytes if any concurrent use cannot be avoided.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Mirtazapine 的其他交互作用
Pimozide 的其他交互作用
常見問題
Can I take Mirtazapine with Pimozide?
MediHelp rates the interaction as contraindicated. Mirtazapine and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Pimozide prolongs the QT interval and can cause torsades de pointes, and mirtazapine may contribute additional QT prolongation. Together they raise the risk of serious ventricular arrhythmia.
How serious is the interaction between Mirtazapine and Pimozide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and select an antidepressant with minimal QT effect if pimozide is required. Check baseline ECG and electrolytes if any concurrent use cannot be avoided.
What other medicines interact with Mirtazapine?
MediHelp also lists interactions of Mirtazapine with, for example, Isocarboxazid, Phenelzine, Procarbazine. The full list is on the Mirtazapine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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