藥物交互作用
Rosuvastatin + Roxadustat
嚴重程度: 中度
Rosuvastatin and Roxadustat: moderate interaction.
最後更新
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摘要
Roxadustat increases rosuvastatin exposure, which raises the risk of dose-related statin adverse effects such as myopathy. Patients with renal impairment are particularly susceptible.
用白話說明這項交互作用的意義
Rosuvastatin and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Rosuvastatin belongs to Cardiovascular; Roxadustat belongs to Miscellaneous.
為什麼會發生
Roxadustat inhibits OATP1B1 and BCRP transporters that handle rosuvastatin.
處置方式
Monitor for muscle symptoms and consider lowering the rosuvastatin dose. Check CK if symptoms develop.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Roxadustat 的其他交互作用
Rosuvastatin 的其他交互作用
常見問題
Can I take Rosuvastatin with Roxadustat?
MediHelp rates the interaction as moderate. Rosuvastatin and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Roxadustat increases rosuvastatin exposure, which raises the risk of dose-related statin adverse effects such as myopathy. Patients with renal impairment are particularly susceptible.
How serious is the interaction between Rosuvastatin and Roxadustat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for muscle symptoms and consider lowering the rosuvastatin dose. Check CK if symptoms develop.
What other medicines interact with Roxadustat?
MediHelp also lists interactions of Roxadustat with, for example, Gemfibrozil, Probenecid, Atorvastatin. The full list is on the Roxadustat page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
