Drug reference
perampanel
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Epileptic Drugs)
Mechanism of action
Noncompetitive antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor on post-synaptic neurons; glutamate is a primary excitatory neurotransmitter in the CNS and is implicated in various neurological disorders caused by neuronal over excitation
Common side effects
- Dizziness
- Somnolence
- Headache
- Fatigue
- Ataxia
- Vertigo
- Irritability
Related conditions
Frequently asked questions
What drug class is perampanel?
perampanel belongs to: Central Nervous System.
How does perampanel work?
Noncompetitive antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor on post-synaptic neurons; glutamate is a primary excitatory neurotransmitter in the CNS and is implicated in various neurological disorders caused by neuronal over excitation
What are the common side effects of perampanel?
Dizziness, Somnolence, Headache, Fatigue, Ataxia, Vertigo, Irritability
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