Drug reference
sodium zirconium cyclosilicate
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Miscellaneous (Miscellaneous)
Mechanism of action
Potassium binder; nonabsorbed zirconium silicate that preferentially captures potassium in exchange for hydrogen and sodium
It increases fecal potassium excretion through binding of potassium in the lumen of the GI tract; binding of potassium reduces the free potassium concentration in the GI lumen, thereby lowering serum potassium level
Common side effects
- Hypokalemia
- edema
Related conditions
Frequently asked questions
What drug class is sodium zirconium cyclosilicate?
sodium zirconium cyclosilicate belongs to: Miscellaneous.
How does sodium zirconium cyclosilicate work?
Potassium binder; nonabsorbed zirconium silicate that preferentially captures potassium in exchange for hydrogen and sodium It increases fecal potassium excretion through binding of potassium in the lumen of the GI tract; binding of potassium reduces the free potassium concentration in the GI lumen, thereby lowering serum potassium level
What are the common side effects of sodium zirconium cyclosilicate?
Hypokalemia, edema
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