Drug interactions
Cefditoren + Sodium zirconium cyclosilicate
Severity: Moderate
Cefditoren and Sodium zirconium cyclosilicate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefditoren pivoxil absorption depends on gastric acidity. Sodium zirconium cyclosilicate can raise gastric pH, which may reduce cefditoren exposure and efficacy.
What this interaction means in plain words
Cefditoren and Sodium zirconium cyclosilicate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefditoren belongs to Anti Bacterial; Sodium zirconium cyclosilicate belongs to Miscellaneous.
Why it happens
Increased gastric pH reduces the pH-dependent dissolution and absorption of oral cefditoren.
What to do
Give cefditoren at least 2 hours before or after sodium zirconium cyclosilicate; monitor for clinical response to the antibiotic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cefditoren
- Aluminum hydroxide + Cefditoren Moderate
- Calcium carbonate + Cefditoren Moderate
- Calcium + Cefditoren Moderate
- Cefditoren + Cholera vaccine Moderate
- Cefditoren + Cimetidine Moderate
- Cefditoren + Dexlansoprazole Moderate
Other interactions of Sodium zirconium cyclosilicate
- Cefpodoxime + Sodium zirconium cyclosilicate Moderate
- Cefuroxime + Sodium zirconium cyclosilicate Moderate
- Crizotinib + Sodium zirconium cyclosilicate Moderate
- Dasatinib + Sodium zirconium cyclosilicate Moderate
- Erlotinib + Sodium zirconium cyclosilicate Moderate
- Itraconazole + Sodium zirconium cyclosilicate Moderate
Frequently asked questions
Can I take Cefditoren with Sodium zirconium cyclosilicate?
MediHelp rates the interaction as moderate. Cefditoren and Sodium zirconium cyclosilicate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefditoren pivoxil absorption depends on gastric acidity. Sodium zirconium cyclosilicate can raise gastric pH, which may reduce cefditoren exposure and efficacy.
How serious is the interaction between Cefditoren and Sodium zirconium cyclosilicate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give cefditoren at least 2 hours before or after sodium zirconium cyclosilicate; monitor for clinical response to the antibiotic.
What other medicines interact with Cefditoren?
MediHelp also lists interactions of Cefditoren with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Cefditoren page.
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