Drug reference

tenofovir alafenamide

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Anti Virals (Hepatits Viruses)

Mechanism of action

Tenofovir alafenamide (AF) is a nucleotide reverse transcriptase inhibitor (NRTI) and a phosphonamidate prodrug of tenofovir Compared with tenofovir disoproxil fumarate (tenofovir DF, Viread), tenofovir AF is a more targeted form of tenofovir that has demonstrated high antiviral efficacy at a dose that is 10 times lower than tenofovir DF, as well

Common side effects

  • Headache
  • Cough
  • Bone mineral density decline
  • Abdominal pain

Related conditions

Frequently asked questions

What drug class is tenofovir alafenamide?

tenofovir alafenamide belongs to: Anti Virals.

How does tenofovir alafenamide work?

Tenofovir alafenamide (AF) is a nucleotide reverse transcriptase inhibitor (NRTI) and a phosphonamidate prodrug of tenofovir Compared with tenofovir disoproxil fumarate (tenofovir DF, Viread), tenofovir AF is a more targeted form of tenofovir that has demonstrated high antiviral efficacy at a dose that is 10 times lower than tenofovir DF, as well

What are the common side effects of tenofovir alafenamide?

Headache, Cough, Bone mineral density decline, Abdominal pain

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