Drug interactions
Aminolevulinic acid + Voriconazole
Severity: Moderate
Aminolevulinic acid and Voriconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral aminolevulinic acid causes photosensitization, and voriconazole is itself phototoxic. Combined use could increase the risk of skin and ocular phototoxic reactions.
What this interaction means in plain words
Aminolevulinic acid and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aminolevulinic acid belongs to Miscellaneous; Voriconazole belongs to Anti Fungals.
Why it happens
Additive phototoxicity (pharmacodynamic).
What to do
Avoid voriconazole or other phototoxic drugs in the 24 hours around aminolevulinic acid use where possible. Advise strict photoprotection.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Other interactions of Aminolevulinic acid
- Acitretin + Aminolevulinic acid Major
- Aminolevulinic acid + Doxycycline Major
- Aminolevulinic acid + Isotretinoin Major
- Aminolevulinic acid + Amiodarone Moderate
- Aminolevulinic acid + Amlodipine-hydrochlorothiazide-valsartan Moderate
- Aminolevulinic acid + Amlodipine-olmesartan-hydrochlorothiazide Moderate
Frequently asked questions
Can I take Aminolevulinic acid with Voriconazole?
MediHelp rates the interaction as moderate. Aminolevulinic acid and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral aminolevulinic acid causes photosensitization, and voriconazole is itself phototoxic. Combined use could increase the risk of skin and ocular phototoxic reactions.
How serious is the interaction between Aminolevulinic acid and Voriconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid voriconazole or other phototoxic drugs in the 24 hours around aminolevulinic acid use where possible. Advise strict photoprotection.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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