Drug interactions
Amlodipine-atorvastatin + Chloroquine
Severity: Minor
Amlodipine-atorvastatin and Chloroquine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine is only a weak CYP3A4 inhibitor, so any increase in amlodipine or atorvastatin exposure is likely small. Clinically meaningful effects are not well documented. Additive QT or myopathy concerns are theoretical with this combination.
What this interaction means in plain words
Amlodipine-atorvastatin and Chloroquine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-atorvastatin belongs to Cardiovascular; Chloroquine belongs to Anti Parasitic.
Why it happens
Possible weak inhibition of CYP3A4 by chloroquine; the clinical relevance is not established.
What to do
No routine adjustment is needed. Monitor blood pressure and report muscle symptoms during prolonged chloroquine use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-atorvastatin
Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Amlodipine-atorvastatin with Chloroquine?
MediHelp rates the interaction as minor. Amlodipine-atorvastatin and Chloroquine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chloroquine is only a weak CYP3A4 inhibitor, so any increase in amlodipine or atorvastatin exposure is likely small. Clinically meaningful effects are not well documented. Additive QT or myopathy concerns are theoretical with this combination.
How serious is the interaction between Amlodipine-atorvastatin and Chloroquine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor blood pressure and report muscle symptoms during prolonged chloroquine use.
What other medicines interact with Amlodipine-atorvastatin?
MediHelp also lists interactions of Amlodipine-atorvastatin with, for example, Amifostine, Apalutamide, Atazanavir. The full list is on the Amlodipine-atorvastatin page.
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