Drug interactions
Amlodipine-atorvastatin + Sotalol
Severity: Minor
Amlodipine-atorvastatin and Sotalol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amlodipine and sotalol both lower blood pressure and together can cause excessive hypotension or bradycardia. The combination is generally tolerated with monitoring.
What this interaction means in plain words
Amlodipine-atorvastatin and Sotalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-atorvastatin belongs to Cardiovascular; Sotalol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic effects: vasodilation from amlodipine and beta blockade from sotalol.
What to do
Monitor blood pressure, heart rate and ECG, including QT interval, when starting or titrating sotalol.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-atorvastatin
Other interactions of Sotalol
- Arsenic trioxide + Sotalol Contraindicated
- Artemether / lumefantrine + Sotalol Contraindicated
- Disopyramide + Sotalol Contraindicated
- Dofetilide + Sotalol Contraindicated
- Dronedarone + Sotalol Contraindicated
- Droperidol + Sotalol Contraindicated
Frequently asked questions
Can I take Amlodipine-atorvastatin with Sotalol?
MediHelp rates the interaction as minor. Amlodipine-atorvastatin and Sotalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Amlodipine and sotalol both lower blood pressure and together can cause excessive hypotension or bradycardia. The combination is generally tolerated with monitoring.
How serious is the interaction between Amlodipine-atorvastatin and Sotalol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and ECG, including QT interval, when starting or titrating sotalol.
What other medicines interact with Amlodipine-atorvastatin?
MediHelp also lists interactions of Amlodipine-atorvastatin with, for example, Amifostine, Apalutamide, Atazanavir. The full list is on the Amlodipine-atorvastatin page.
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